Breathing Symptoms Clinical Study Results | CAYSTON®

CAYSTON may help you breathe better

CAYSTON was studied in a clinical trial with 164 people with CF and Pa lung infection who were 7 years of age and older, with an FEV1 of 25% to 75% predicted. Patients were not on antibiotics for at least 28 days before starting the study. During the study, 80 people received CAYSTON and 84 people received placebo (a salt solution with no medication in it) 3 times a day for 28 days by inhalation with the Altera® Nebulizer System. Every person studied used an inhaled bronchodilator (a medicine used to relax and open your airways) prior to taking CAYSTON or placebo.9

The study looked at the effect of CAYSTON compared to placebo on:

  • Breathing symptoms, such as coughing, wheezing, and sputum production. Changes in respiratory symptoms were assessed using a questionnaire that asks patients to report on symptoms like coughing, wheezing, and sputum production
  • Lung function, as measured by FEV1 (L)
Group of monsters representing Pseudomonas aeruginosa

CAYSTON provided results that people with CF and Pa felt through improved breathing symptoms such as coughing, wheezing, and mucus production.

In the clinical study, people with CF and Pa who used CAYSTON reported statistically significant improvement vs placebo in breathing symptoms like coughing, wheezing, and mucus production on Day 28.

Improvements in breathing symptoms were seen in both the adult and pediatric people studied but were smaller in the adults.

Two weeks after completion of treatment, people treated with CAYSTON still had improved breathing symptoms compared to those who took placebo. However, the difference was smaller.

Click here for a list of common side effects.

KC, treated with CAYSTON

“I really noticed a difference in my respiratory symptoms after 28 days on CAYSTON… when I'm on CAYSTON, I don't wheeze or cough up as much sputum.”

KC, age 19, TREATED WITH CAYSTON

(Individual results may vary.)

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